$119 billion 
 

The "(t)otal annual cost of morbidity-related productivity losses attributable to" major depressive disorder among U.S. adults, according to an article in the American Journal of Preventive Medicine -- Morbidity-related productivity losses from major depressive disorder among U.S. adults. This equates to $5,824 "per affected adult in 2024."

Inability to work costs accounted for 44% of total productivity losses, followed by presenteeism (33%), absenteeism (18%), and household productivity loss (5%). Total productivity loss costs and per-person loss costs differed by sex.